You can choose to do UWorld questions randomly, by subject, or a hybrid approach where you start by subject but become more random over time which is more like boards. 

Here's how to select subject-by-subject.

Immunology

Main Divisions
Select All Main Divisions
Sub Divisions
Select Allergy & Immunology

Microbiology - “Bugs”

Main Divisions
Select All Main Divisions
Unselect Pharmacology
Sub Divisions
Select Infectious Diseases

Microbiology - “Drugs”

Main Divisions
Select Pharmacology
Sub Divisions
Select Infectious Diseases

Heme/Onc - Physiology

Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Hematology & Oncology

Heme/Onc - Path/Pharm

Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Hematology & Oncology

Respiratory - Physiology

Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Pulmonary & Critical Care

Respiratory - Path/Pharm

Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Pulmonary & Critical Care

Cardiology - Physiology

Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Cardiovascular System
Cardiology - Path/Pharm
Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Cardiovascular System

Renal - Physiology

Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Renal, Urinary Systems & Electrolytes

Renal - Path/Pharm

Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Renal, Urinary Systems & Electrolytes

Endocrine - Physiology

Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Endocrine, Diabetes & Metabolism

Endocrine - Path/Pharm

Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Endocrine, Diabetes & Metabolism

GI - Physiology

Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Gastrointestinal & Nutrition

GI - Path/Pharm

Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Gastrointestinal & Nutrition
Neuro - Physiology
Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Nervous System
Select Ophthalmology

Neuro - Path/Pharm

Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Nervous System
Select Ophthalmology

Psychiatry

Main Divisions
Select All Main Divisions
Sub Divisions
Select Psychiatric/Behavioral & Substance Abuse

Reproductive - Physiology

Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Female Reproductive
Select Pregnancy, Childbirth & Puerperium
Select Male Reproductive

Reproductive - Path/Pharm

Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Female Reproductive
Select Pregnancy, Childbirth & Puerperium
Select Male Reproductive

MSK - Physiology

Main Divisions
Select All Main Divisions
Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Rheumatology/Orthopedics & Sports
MSK - Path/Pharm
Main Divisions
Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
Select Rheumatology/Orthopedics & Sports

Biostats & Epidemiology

Main Divisions
Select All Main Divisions
Sub Divisions
Select Biostatistics & Epidemiology

Behavioral science

Main Divisions
Select Behavioral science
Sub Divisions
Select All Sub Divisions
Unselect Psychiatric

Pathology

Main Divisions
Select Histology
Sub Divisions
Select All Sub Divisions


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