You can choose to do UWorld questions randomly, by subject, or a hybrid approach where you start by subject but become more random over time which is more like boards. 

Here's how to select subject-by-subject.

Immunology

Main Divisions
     Select All Main Divisions
Sub Divisions
     Select Allergy & Immunology

Microbiology - “Bugs”

Main Divisions
     Select All Main Divisions
     Unselect Pharmacology
Sub Divisions
     Select Infectious Diseases

Microbiology - “Drugs”

Main Divisions
     Select Pharmacology
Sub Divisions
     Select Infectious Diseases

Heme/Onc - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Hematology & Oncology

Heme/Onc - Path/Pharm

Main Divisions
     Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Hematology & Oncology

Respiratory - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Pulmonary & Critical Care

Respiratory - Path/Pharm

Main Divisions
     Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Pulmonary & Critical Care

Cardiology - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Cardiovascular System

Cardiology - Path/Pharm

Main Divisions
     Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Cardiovascular System

Renal - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Renal, Urinary Systems & Electrolytes

Renal - Path/Pharm

Main Divisions
    Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
    Select Renal, Urinary Systems & Electrolytes

Endocrine - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Endocrine, Diabetes & Metabolism

Endocrine - Path/Pharm

Main Divisions
     Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Endocrine, Diabetes & Metabolism

GI - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Gastrointestinal & Nutrition

GI - Path/Pharm

Main Divisions
    Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Gastrointestinal & Nutrition

Neuro - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Nervous System
     Select Ophthalmology

Neuro - Path/Pharm

Main Divisions
     Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Nervous System
     Select Ophthalmology

Psychiatry

Main Divisions
     Select All Main Divisions
Sub Divisions
     Select Psychiatric/Behavioral & Substance Abuse

Reproductive - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Female Reproductive
     Select Pregnancy, Childbirth & Puerperium
     Select Male Reproductive

Reproductive - Path/Pharm

Main Divisions
     Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Female Reproductive
     Select Pregnancy, Childbirth & Puerperium
     Select Male Reproductive

MSK - Physiology

Main Divisions
     Select All Main Divisions
     Unselect Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Rheumatology/Orthopedics & Sports

MSK - Path/Pharm

Main Divisions
     Select Pathology, Pathophysiology, and Pharmacology
Sub Divisions
     Select Rheumatology/Orthopedics & Sports

Biostats & Epidemiology

Main Divisions
     Select All Main Divisions
Sub Divisions
     Select Biostatistics & Epidemiology

Behavioral science

Main Divisions
     Select Behavioral science
Sub Divisions
     Select All Sub Divisions
     Unselect Psychiatric

Pathology

Main Divisions
     Select Histology
Sub Divisions
     Select All Sub Divisions


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